Increase your Tenacity and Slow Resistance for each summoner spell on cooldown. Immediately after casting a Summoner Spell, gain a larger burst of Tenacity and Slow Resistance for a moderate duration.
You get free boots at 10 min. but you cannot buy boots before then. These boots give additional MS. For each takedown you acquire the boots 30s sooner.
Start the game with 3 Minion Dematerializers. Killing minions with the item gives permanent bonus damage vs. that minion type.
Offense
+1-10% CDR
Flex
+6 Armor or 8 MR (match-up)
Defense
+15-90 Health
WhyGrasp of the Undying
Grasp on Poppy allows her to trade incredibly well in lane and sustain a ton of damage thanks to her massive resist stacking. The heal and bonus health from Grasp make every point of health much stronger due to those resists.
WhyDemolish
Demolish is a fantastic rune choice for snowball early gank kills for a quick team gold lead.
WhyConditioning
Conditioning's duo resist buff at 10mins synergizes well with the additional resists from [W] making you incredibly tanky and resilient in the mid-game.
WhyUnflinching
Poppy's biggest pitfall is her lack of mobility. She can be a threat to squishy champions if she is able to stick to them. Unflinching's Tenacity/Slow Resist allows you to dive the backline and stick to them for kill threat.
WhyMagical Footwear
Magical Footwear's raw gold value is huge for hitting your crucial mid-game 2 item power-spike.
WhyMinion Dematerializer
Minion Dematerializer is great for empowering your ability to shove the lane at match top laner roams during jungle skirmishes.