Gain increasing amounts of AD or AP, Adaptive over the course of the game.
+9% Attack Speed
+5 AD or 9 AP
Lethal Tempo on Twitch allows you to take over take-game teamfights when paired with the massive attack range and damage from your [R], to solo win the game.
Triumph acts as a largely mid-fight heal for late game teamfights where you are able to hit the majority of the enemy team with [R].
Twitch is an AD Carry that naturally relies on getting as many auto attacks in as possible for extra damage. Alacrity will also help you build passive stacks faster in the early game for [E] burst damage.
WhyCoup De Grace
Coup De Grace is the go-to rune for reliable bonus damage. Paired with the burst of [E], Twitch's damage can scale incredibly well with a small lead.
If you're playing into a number of tanks (Jungle, Top, Support) Cut Down can be a great alternative thanks to your ability to hit multiple target in a teamfight with [R].
The bonus AD granted from Absolute Focus is huge for empowering your damage opener when coming out of stealth as well as those late game teamfights before you are targeted.
Gathering Storm is your late-game insurance policy. In a 40min+ game you will be bale to potentially take over a teamfight with a well positioned [R].