All movement Speed bonuses are 8% more effective on you.
Offense
+1-10% CDR
Flex
+5 AD or 9 AP
Defense
+6 Armor or 8 MR (match-up)
WhyPredator
Predator on Vlad allows you to make massive roams into the side lines to get a quick lead and snowball with your item efficiency. The extra burst of speed is great for initiating fights as well.
WhyTaste of Blood
Taste of Blood further empowers your sustain lane harass, allowing you to constantly out trade your lane opponent.
WhyEyeball Collection
Eyeball Collection's extra AP means not only more damage but more tankiness furthering your early lead.
WhyRavenous Hunter
Ravenous Hunter makes Vladimir an insane teamfighter and skirmisher when you're able to pick up a few stacks, empowering your healing even further.
WhyNimbus Cloak
Nimbus Cloak's massive movement speed boost is great for empowering your ability to dive the backline and kill them quickly after you engage with an [R] cast.
WhyCelerity
Celerity's massive movement speed boost while Predator and Nimbus Cloak are active allows you to front-load a lot of your damage into a huge burst on important targets.