Mid lane roaming and massive early skirmish power.
Burst damage and target access
Add an active effect to your boots that grants a large boost of MS and causes your next attack or spell to deal bonus adaptive damage.
Recover health when you damage an enemy champion.
Collect eyeballs for champion and ward takedowns. Gain permanent AD or AP, Adaptive for each eyeball plus bonus upon collection completion.
Heal for a percentage of damage dealt with your abilities. Increases with each unique takedown.
Empowered abilities and resource manipulation
Shortly after using your Ultimate, gain a decaying Movement Speed increase that lasts for 3s and allows you to pass through units.
All movement Speed bonuses are 8% more effective on you.
+5 AD or 9 AP
+6 Armor or 8 MR (match-up)
Predator on Vlad allows you to make massive roams into the side lines to get a quick lead and snowball with your item efficiency. The extra burst of speed is great for initiating fights as well.
Taste of Blood further empowers your sustain lane harass, allowing you to constantly out trade your lane opponent.
Eyeball Collection's extra AP means not only more damage but more tankiness furthering your early lead.
Ravenous Hunter makes Vladimir an insane teamfighter and skirmisher when you're able to pick up a few stacks, empowering your healing even further.
Nimbus Cloak's massive movement speed boost is great for empowering your ability to dive the backline and kill them quickly after you engage with an [R] cast.
Celerity's massive movement speed boost while Predator and Nimbus Cloak are active allows you to front-load a lot of your damage into a huge burst on important targets.