Difficult AP matchups.
Burst damage and target access
Hitting a champion with 3 separate attacks or abilities in 2s deals bonus adaptive damage.
Gain a burst of Lethality and Magic Penetration after using a dash, leap, blink, teleport, or on leaving stealth.
Collect eyeballs for champion and ward takedowns. Gain permanent AD or AP, Adaptive for each eyeball plus bonus upon collection completion.
Unique champion takedowns grant permanent out of combat MS.
Empowered abilities and resource manipulation
Gain a magic damage shield when taken to low health by magic damage.
Your first ability hit every 20s burns champions.
Offense
+5 AD or 9 AP
Flex
Defense
+6 Armor or 8 MR (match-up)
Like Thunderlords, Electrocute is quite easy for Zed to proc and gives him great kill threat.
Sudden Impact is easily procced by Zed from [W] or [R] granting the Lethality needed for the kill.
Zed is all about the kills and Eyeball Collection rewards you for doing so by granting you more damage.
Movement Speed is a key stat for hunting down and finding an angle on your prey and Relentless Hunt helps you find those openings.
Nullifying Orb is a key rune in this loadout as it's an integral part in surviving hard AP matchups. Think of it as a free hexdrinker.
Scorch's extra bit of early game damage can be incredibly useful to chip away at your opponent with [Q] before 6 so that you can all-in with [R].