Vel'Koz
Knowledge Through Disintegration
Lane harassment and consistent damage output.
Inspiration
Creative tools and rule bending
Glacial AugmentImmobilizing an enemy champion will cause 3 glacial rays that slow nearby enemies and reduce their damage to your allies.
Magical FootwearYou get free boots at 12 min but you cannot buy boots before then. Each
takedown you get makes your boots come 45s sooner.
Biscuit DeliveryGain a free Biscuit every 2 min, until 6 min. Consuming or selling a Biscuit permanently increases your max health and restores health.
Cosmic Insight+
18 Summoner Spell Haste
+10 Item Haste
Domination
Burst damage and target access
Cheap ShotDeal bonus true damage to enemy champions with
impaired movement or actions .- Ingenious Hunter
Unique
takedowns grant permanent ItemHaste (includes Trinkets).
Adaptive Force
+9
Adaptive Force Adaptive Force
+9
Adaptive Force
Why Glacial Augment
The slow from Glacial Augment is fantastic for setting up an easy [E] and allowing you to kill any target to control the fight.
Why Magical Footwear
Magical Footwear's raw gold value helps you accelerate your mid game item efficiency.
Why Biscuit Delivery
Biscuit Delivery is great for sustaining your laning and getting you to easy teamfights where you can take over.
Why Cosmic Insight
Cosmic Insight's general utility means more damage output and spell rotations.
WhyCheap Shot
Cheap Shot pairs well with the slows from Glacial Augment for extra damage.
WhyIngenious Hunter
Ingenious Hunter is great when paired with the slow item actives for Glacial Augment.
Deadly Disintegration Damage
Lane harassment and consistent damage output.
Sorcery
Empowered abilities and resource manipulation
Arcane CometDamaging a champion with an ability hurls a damaging comet at their location.
Manaflow BandHitting an enemy champion with an ability permanently increases your maximum mana by 25, up to 250 mana.
After reaching 250 bonus mana, restore 1% of your missing mana every 5 seconds.
TranscendenceGain bonuses upon reaching the following levels:
Level 5: +5Ability Haste
Level 8: +5Ability Haste
Level 11: On Champion takedown, reduce the remaining cooldown of basic abilities by 20%.
ScorchYour first damaging ability hit every 10s burns champions.
Inspiration
Creative tools and rule bending
- Magical Footwear
You get free boots at 12 min but you cannot buy boots before then. Each
takedown you get makes your boots come 45s sooner. - Cosmic Insight
+
18 Summoner Spell Haste
+10 Item Haste
Adaptive Force
+9
Adaptive Force Adaptive Force
+9
Adaptive Force 
Health Scaling
+10-180 Health (based on level)
Why Arcane Comet
Arcane Comet is a great keystone choice for Vel'koz as it reliably empowers his ability to poke in lane. Thanks to the slow from [Q] and [R], and the small knockup from [E], you should be able to reliably land Comet if you are hitting your abilities.
Why Manaflow Band
The added poke sustain thanks to the extra mana from Manaflow Band is fantastic for keeping up lane pressure for a kill or zoning the enemy off a turret during a siege.
Why Transcendence
Transcendence allows you to hit 35% CDR with just Morello's and Cosmic Insight, allows you to spam your abilities for poke damage and kill pressure.
Why Scorch
Scorch further empowers your ability to poke and harass in the laning phase. If you're able to proc Scorch on cooldown several times before hitting level 6, you should be able to keep your lane opponent in kill range when you skill [R].
WhyMagical Footwear
Magical Footwear is a great rune choice on just about any champion largely for its raw gold value with no input. Think of it as effectively gaining a kill's worth of gold at 10min.
WhyCosmic Insight
Cosmic Insight is an all-around great rune choice on any champion, especially poke champions who are constantly looking to deal damage from range when their abilities come off cooldown.