Mel

Glutton for Punishment

Lane harassment and consistent damage output.

Empowered abilities and resource manipulation

Arcane Comet

Damaging a champion with an ability hurls a damaging comet at their location.
Manaflow Band

Hitting an enemy champion with an ability permanently increases your maximum mana by 25, up to 250 mana.

After reaching 250 bonus mana, restore 1% of your missing mana every 5 seconds.
Transcendence

Gain bonuses upon reaching the following levels:
Level 5: +5 Ability Haste
Level 8: +5 Ability Haste
Level 11: On Champion takedown, reduce the remaining cooldown of basic abilities by 20%.
Scorch

Your first damaging ability hit every 10s burns champions.

Improved attacks and sustained damage

Presence of Mind

Restore a small amount of mana or energy when damaging an enemy champion. Takedowns restore mana or energy.
Legend: Haste

Takedowns on enemies grant permanent Basic Ability Haste.

Mel is a champion that accels at long-range repeated poke, making Comet a reliable socurce of early game damage.

Manaflow Band is a generally stable and useful rune choice for mages, especially when you are repeatedly using your abilities.

More CDR means more ability casts and more casts means more poke.

Scorch pairs well with Comet to deal a lot of harassment damage early game.

Mel is a champion that relies on her abilities to deal damage, so Presence of Mind is a great choice to help her sustain.

Legend: Haste gives you much higher uptime on your basic abilities and allows Mel to deal repeated consistent damage.