Malzahar
Their Time is Short
Lane harassment and consistent damage output.
Inspiration
Creative tools and rule bending
Unsealed SpellbookSwap Summoner Spells while out of combat. Swapping to unique Summoner Spells will increase the rate at which you can make future swaps.
Triple TonicUpon reaching level 3, gain an Elixir of Avarice.
Upon reaching level 6, gain an Elixir of Force.
Upon reaching level 9, gain an Elixir of Skill.
Jack Of All TradesFor each different stat gained from items, gain one Jack stack. Each stack grants you
1 Ability Haste .
Gain bonusAdaptive Force at 5 and 10 stacks.
Cosmic Insight+
18 Summoner Spell Haste
+10 Item Haste
Sorcery
Empowered abilities and resource manipulation
Manaflow BandHitting an enemy champion with an ability permanently increases your maximum mana by 25, up to 250 mana.
After reaching 250 bonus mana, restore 1% of your missing mana every 5 seconds.
TranscendenceGain bonuses upon reaching the following levels:
Level 5: +5Ability Haste
Level 8: +5Ability Haste
Level 11: On Champion takedown, reduce the remaining cooldown of basic abilities by 20%.
Adaptive Force
+9
Adaptive Force Adaptive Force
+9
Adaptive Force 
Health Scaling
+10-180 Health (based on level)
Why Unsealed Spellbook
Unsealed Spellbook allows you to heavily abuse your Summoner CDR with Lucidity Boots for **aggressive picks with Flash->[R]**. It also allows you to swap between Cleanse/Ghost and TP for when you need lane pressure.
Why Triple Tonic
Perfect Timing is a great rune in situations where enemy mid has dive potential on you and you want to make the out-play. It also allows you to buy an earlier/cheaper Zhonya's or just sell off the Broken Stopwatch for the free gold.
Why Jack Of All Trades
Minion Dematerializer on Malzahar is great for empowering your ability to wave clear for optimal recall timing and roams to the side lanes.
Why Cosmic Insight
The extra bit of CDR and Summoner CDR from Cosmic Insight even further enables your potential to abuse your short Flash cooldown.
WhyManaflow Band
Manaflow Band is incredibly strong for empowering your early-to-mid game push sustain
WhyTranscendence
The bonus CDR granted from Transcendence is massively for empowering your mid-game teamfight control.
Suppression Into Oblivion
Lane harassment and consistent damage output.
Sorcery
Empowered abilities and resource manipulation
Summon AeryYour attacks and abilities send Aery to a target, damaging enemies or shielding allies.
- Manaflow Band
Hitting an enemy champion with an ability permanently increases your maximum mana by 25, up to 250 mana.
After reaching 250 bonus mana, restore 1% of your missing mana every 5 seconds. 
CelerityAll
Move Speed bonuses are 7% more effective on you and gain1% Move Speed .
ScorchYour first damaging ability hit every 10s burns champions.
Inspiration
Creative tools and rule bending
- Cosmic Insight
+
18 Summoner Spell Haste
+10 Item Haste 
Magical FootwearYou get free boots at 12 min but you cannot buy boots before then. Each
takedown you get makes your boots come 45s sooner.
Adaptive Force
+9
Adaptive Force Adaptive Force
+9
Adaptive Force Health Scaling
+10-180 Health (based on level)
Why Summon Aery
Malzahar's repeated damage with refreshing [E] with [Q] and the DoT from [R] is great for lane harass and constant damage output.
Why Manaflow Band
Manaflow Band allows you to keep up your mid-game damage output and harass with a sustained mana pool and easy stacking with [E].
Why Celerity
Celerity is a great rune on Malzahar largely thanks to the passive Movement Speed. The extra bit of speed allow you to get into range of that clutch [R] that you might not otherwise be able to get.
Why Scorch
The option here is really a personal preference. Scorch is great for lane harass and early fights while Gathering Storm is great for scaling and pairs well with Magic Penetration. If it looks like your game might be stalled out by wave clearer (Anivia etc.), you can take Gathering Storm for scaling.
WhyCosmic Insight
Malzahar loves CDR for both his [R] and harassing/shoving in lane with [E]. Assuming you've completed Morello's, you'll already be at **35% CDR and incredibly strong at 10min**.
WhyMagical Footwear
Magical Footwear is a great rune choice for simply saving money so you can hit your damage power-spikes that much sooner. If you prefer to rush Boots to catch your targets in [R], take Perfect Timing for a cheaper Zhonya's.